It represents the main part of the PIF and is divided into two parts:

Part A: Information on the safety of the cosmetic product (quantitative and qualitative composition, physicochemical characteristics and stability, microbiological quality of substances, mixtures and the finished product, impurities, traces and information on the packaging material, normal and reasonably foreseeable use, exposure cosmetic product, exposure to substances, description of the toxicological hazard of each ingredient in the finished product, notification of unwanted and serious unwanted effects).

Part B: Safety assessment of the cosmetic product (conclusion of the safety assessment, labeling with warnings and instructions for use, scientific reasoning, credentials of the safety assessor and approval of part B).